Please note: The University of Texas Health Science Center at San Antonio will now be called "UT Health San Antonio."

Personalized Molecular Medicine

The Master of Science in Personalized Molecular Medicine (PMM) degree program will uniquely position new graduates to join the work force with the skills necessary to participate fully in the next generation of “patient-powered” research and treatment. The PMM program will train students in current personalized medicine approaches as well as teach students the knowledge and skills required to explore molecular medicine pathways that will be targeted in the future to expand and refine personalized treatment strategies. Personalized or Precision Medicine will be the norm for medicine in the future and the PMM program will ensure that graduates fully engage as active participants in the evolution of this approach to medicine. Students will gain foundational training in biological systems, molecular mechanisms, and cutting edge translational technologies. 

Training will include next generation molecular technology to devise and implement personalized strategies to prevent and treat human diseases based on individual susceptibilities through the study of complex and integrated biological systems. Students will receive first-hand experience in the use of the latest technologies in next generation sequencing, single cell analysis, computational biology, epigenomics, proteomics, drug design, animal models of human diseases, systems approaches, as well as instruction in “mining” the multitude of human disease databases such as The Cancer Genome Atlas (TCGA). Programmatic faculty members participate actively in systems biology research focused on understanding a range of human disorders including cancer, developmental defects, hormone dysregulation, and metabolic disorders. Students will participate in didactic classroom instruction, team based learning, and hands-on laboratory training with a choice between a Thesis/Research or Course-Based plan of study.

Program Admission Requirements:

The admission requirements for the PMM degree program are listed below. All of the required application information including Official Transcripts from all institutions attended, must be submitted in order for an applicant to be considered by the PMM program Admissions Committee. In general, students should have a sufficient educational background in the biological or biochemical sciences prior to admission to the program.

1. A baccalaureate degree from an accredited institution in the United States or proof of an equivalent degree and training from a foreign institution.
2. Grade point average (GPA): No lower than B (e.g., 3.00 in a 4.00 system)
3. GRE scores: A satisfactory score for the Graduate Record Examination (GRE), as recommended by the Graduate School of Biomedical Sciences (GSBS), is a minimum of the 50th percentile for the verbal and quantitative portions of the GRE taken within five years prior to the date of the application. MCAT scores can be substituted for GRE scores.
4. TOEFL scores: For applicants from countries where English is not the native language, a minimum score on the Test of English as a Foreign Language (TOEFL) of 560 (paper test), 220 (computer test), or 68 (internet test) is expected.
5. Letters of recommendation (three) attesting to the applicant's readiness for graduate level studies.
6. Coursework: Biology for science majors with lab; Organic and inorganic chemistry with labs.

Highly recommended:
1. Coursework: Physics; Calculus; Upper level courses in cell biology, biochemistry, genetics, or molecular biology.
2. Research experience

Program-specific Degree Requirements:

A minimum of 36 SCH and a minimum overall GPA of 3.0 is required for the M.S. degree. In addition, students must successfully complete all the course requirements. Students choosing the Course Based Plan must pass the final oral examination. Students choosing the Thesis/Research Plan must register for MMED 6098, Thesis, for at least one semester prior to graduation and successfully defend a thesis. All students must be recommended by their program COGS for approval of their degree to the Dean of the Graduate School of Biomedical Sciences.

First Year:
First-year students shall take the required PMM courses (Core Curriculum) and choose a degree plan (Course-Based or Thesis/Research Plan). All students will register for Seminars in Molecular Medicine (MMED 6091). Students must enroll for 9 semester credit hours per semester.
Course-Based Plan: Students will complete required courses, research practicum, and practicum reports.
Thesis/Research Plan: In addition to completing the required courses, students will complete two laboratory rotations, and must select a research area of interest and a Thesis/Research Advisor.

Second Year:
Course-Based Plan: Students will complete additional course requirements as well as the Research Practicum and Practicum Reports. Students may complete additional elective courses as needed to meet final credit hours required for graduation. Students will complete their final oral examination based on course and practicum material.
Thesis/Research Plan: Student will choose a Thesis/Research Committee and gain approval of their research proposal to advance to candidacy. Student will complete their research, write their thesis, and defend their thesis in a final presentation and oral examination.

PMM Plan of Study


For a list of faculty, click here 

Program Directors:

P. Renee Yew, Ph.D.

Program Director


Z. Dave Sharp, Ph.D.

Program Co-Director


Academic Program Coordinator for PMM:

Magdalene Madla


Application Deadline for Fall Admission:

Priority deadline: April 1

Final deadline: May 31