Please note: The University of Texas Health Science Center at San Antonio will now be called "UT Health San Antonio."

Search Program Faculty/Research

Seema Ahuja, M.D.

500477

RESEARCH

Dr Ahuja received her M.D. from the Armed Forces Medical College, Pune, India. She is presently a Professor at the Department of Medicine, University of Texas Health Science Center at San Antonio, Texas, USA. Her postdoctoral training was at the National Institute of Diabetes and Digestive and Kidney Diseases and the Laboratory of Host Defenses, National Institutes of Health,Bethesda MD. Her long term goal is to elucidate the role of chemokines and chemokine receptors in generation of host immune responses using murine models of human diseases such as rheumatoid arthritis, Kawasaki's Disease and atherosclerosis.

Selected Publications

Wagner BT, Tan C, Barnes JL, Ahuja SS, Davis TL, Gorin Y, Jimenez F. Nephrogenic systemic fibrosis: evidence for oxidative stress and bone marrow-derived fibrocytes in skin, liver, and heart lesions using a 5/6 nephrectomy rodent model Am J Pathol 2012 Dec;181(6):1941-1952.

Zamilpa R, Ibarra J, de Castro Bras LE, Ramirez TA, Nguyen N, Halade GV, Zhang J, Dai Q, Dayah T, Chiao YA, Lowell W, Ahuja SS, D''Armiento J, Jin YF, Lindsey ML. Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction J Mol Cell Cardiol 2012 Nov;53(5):599-608.

Martinez HG, Quinones MP, Jimenez F, Estrada C, Clark KM, Suzuki K, Miura N, Ohno N, Ahuja SK, Ahuja SS. Important role of CCR2 in a murine model of coronary vasculitis BMC Immunol 2012 Oct;13(1):56-56.

Kalkonde YV, Shelton R, Villarreal M, Sigala J, Mishra PK, Ahuja SS, Barea-Rodriguez E, Moretti P, Ahuja SK. The CC chemokine receptor 5 regulates olfactory and social recognition in mice Neuroscience 2011 Dec;197:153-161.

Martinez HG, Quinones MP, Jimenez F, Estrada CA, Clark K, Muscogiuri G, Sorice G, Musi N, Reddick RL, Ahuja SS. Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome Diabetologia 2011 Oct;54(10):2660-2668.

Ibarra JM, Quinones MP, Estrada CA, Jimenez F, Martinez HG, Ahuja SS. CD8alpha+ dendritic cells improve collagen-induced arthritis in CC chemokine receptor (CCR)-2 deficient mice Immunobiology 2011 Sep;216(9):971-978.

Chiao Y, Dai Q, Zhang J, Lin J, Lopez EF, Ahuja SS, Chou Y-M, Lindsey ML, Jin Y. Multi-analyte profiling reveals matrix metalloproteinase-9 and monocyte chemotactic protein-1 as plasma biomarkers of cardiac aging Circul Cardovasc Genet 2011 Aug;4(4):455-462.

Ibarra JM, Jimenez F, Martinez HG, Clark K, Ahuja SS. MMP-Activated Fluorescence Imaging Detects Early Joint Inflammation in Collagen-Antibody-Induced Arthritis in CC-Chemokine Receptor-2-Null Mice, In-Vivo Int J Inflam 2011 Jun;2011:691587-691587.

Zamilpa R, Kanakia R, Cigarroa J, Dai Q, Escobar GP, Martinez HM, Jimenez F, Ahuja S, Lindsey ML. CC Chemokine Receptor 5 Deletion Impairs Macrophage Activation and Induces Adverse Remodeling Following Myocardial Infarction. (Note: This article was featured on the www.MDLinx.com site on 2/21/11.) Am J Physiol Heart Circ Physiol 2011 Apr;300(4):H1418-H1426.

Li G, Biju KC, Xu X, Zhao Q, Valente AJ, He W, Reddick RL, Freeman GL, Ahuja SS, Clark R, Li S. Enhanced expression of LCR alpha in macrophages ameliorates atherosclerosis in LDL receptor deficient mice Gene Therapy 2011 Mar;18(8):835-841.

Kalkonde YV, Morgan WW, Sigala J, MAFFI SK, Condello C, Kuziel W, Ahuja SS, Ahuja SK. Chemokines in the MPTP model of Parkinsons disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration Brain Res 2007 Jan;1128(1):1-11.

Professor

Education

B.M./B.S., Medicine, Armed Forces Medical College, 1984

Contact

Phone: (210) 218-1688

Email: ahuja@uthscsa.edu