Please note: The University of Texas Health Science Center at San Antonio will now be called "UT Health San Antonio."

Search Program Faculty/Research

Muhammed Abdul-Ghani, M.D., Ph.D.



The seminal studies of Dr. Muhammad Abdul-Ghani have helped to define the role of progressive beta cell failure in the evolution from prediabetes to T2DM and to elucidate the contribution of mitochondrial dysfunction in the development of insulin resistance and T2DM.

Selected Publications

Triplitt C, Solis-Herrera C, Cersosimo E,Abdul-Ghani M, Defronzo RA. Empagliflozin and linagliptin combination therapy for treatment of patients with type 2 diabetes mellitus. Expert Opin Pharmacother. 2015 [Epub ahead of print]

Abdul-Ghani M, DeFronzo RA. The place of renal sodium-glucose co-transport in the management of type 2 diabetes mellitus. Am J Physiol. 2015 (ahead of print).

Kanat M, DeFronzo RA and Abdul-Ghani M, Treatment of prediabetes. World J Diabetes. 6:1207-22, 2015

Abdul-Ghani MA, Puckett C, Triplitt C, Maggs D, Adams J, Cersosimo E, DeFronzo RA Initial Combination Therapy with Metformin/Pioglitazone/Exenatide is More Effective Than Sequential Add-On Therapy in Subjects with New Onset Diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes (EDICT): A Randomized Trial. Diabetes Obes Metab. 17:268-75, 2015

Winnier DA, Fourcaudot M, Norton L, Abdul-Ghani MA, Hu SL, Farook VS, Coletta DK, Kumar S, Puppala S, Chittoor G, Dyer TD, Arya R, Carless M, Lehman DM, Curran JE, Cromack DT, Tripathy D, Blangero J, Duggirala R, Göring HH, DeFronzo RA, Jenkinson CP. Transcriptomic Identification of ADH1B as a Novel Candidate Gene for Obesity and Insulin Resistance in Human Adipose Tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES). PLoS One. 10:e0119941, 2015

Valaparla SK; Gao F; Daniele G; Abdul-Ghani M; Clarke GD. Fiber orientation measurements by diffusion tensor imaging improve hydrogen-1 magnetic resonance spectroscopy of intramyocellular lipids in human leg muscles Journal of Medical Imaging 2: 026002, 2015

Associate Professor



Ph. D., Medicine, Hebrew University, 1991

M.D., Hebrew University, 1990

BMedSci, Hebrew University, 1984

B.S., Biology, Hebrew University 1982



Phone: (210) 557-1157