Dr. Jaclyn Hung's laboratory works to understand the mechanisms involved in the maintenance of the stem-like phenotype in pediatric cancer.
Sugalski A, Davis M, Prasannan L, Saldivar V, Hung JY, Tomlinson GE. Clinical, histologic, and genetic features of mesothelioma in a 7-year-old child. Pediatr Blood Cancer. 2013 Jan;60(1):146-8.
Sanchez-Diaz PC, Hsiao TH, Chang JC, Yue D, Tan MC, Chen HI, Tomlinson GE, Huang Y, Chen Y, Hung JY. De-regulated microRNAs in pediatric cancer stem cells target pathways involved in cell proliferation, cell cycle and development. PLoS One. 2013 Apr 17;8(4):e61622.
Chen TT, Rakheja D, Hung JY, Hornsby PJ, Tabaczewski P, Malogolowkin M, Feusner J, Miskevich F, Schultz R, Tomlinson GE. Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor. Pediatr Blood Cancer. 2009 Dec;53(6):1040-7.
Sanchez-Diaz PC, Burton TL, Burns SC, Hung JY, Penalva LO. Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy. BMC Cancer. 2008 Sep 30;8:280.
Ho MM, Ng AV, Lam S, Hung JY. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 2007 May 15;67(10):4827-33.