Please note: The University of Texas Health Science Center at San Antonio will now be called "UT Health San Antonio."

Search Program Faculty/Research

Eugenio Cersosimo, M.D., Ph.D.

E.-cersosimo-photo cropped


Eugenio Cersosimo, MD, PhD is currently the medical director of clinical research at the Texas Diabetes Institute and an associate professor of medicine at the University of Texas Health Science Center in San Antonio, Texas. He is board certified in endocrinology, diabetes and metabolism and maintains an active practice in the adult outpatient clinic in San Antonio. Dr. Cersosimo graduated from medical school at the Universidade Federal Fluminense in Rio de Janeiro, Brazil in 1975 and obtained a doctorate degree in physiology at Vanderbilt University in Nashville, Tennessee in 1986. 

He completed his training in internal medicine and endocrinology, diabetes & metabolism in the Clinician Investigator Tract at the Mayo Clinic, Rochester, Minnesota in 1994. He started his academic career as an assistant professor of medicine at the State University of New York at Stony Brook, NY and in 2001 transferred to his current position at the University of Texas Health Science Center in San Antonio. 

Dr. Cersosimo has authored more than 60 original manuscripts and has received numerous research grants and awards from the National Institutes of Health, Juvenile Diabetes Foundation, American Diabetes Association, Kronkosky Foundation, Howard Hughes Institute, and from various pharmaceutical companies. Presently, he is directly involved in and supervises more than 20 different research projects in areas of his greatest interest: glucose regulation, the entero-pancreatic axis, and insulin therapy & insulin resistance with a focus on cardiovascular and renal complications.

Selected Publications

Cersosimo E, Solis-Herrera C, Triplitt C. Inhibition of renal glucose reabsorption as a novel treatment for diabetes patients J Bras Nefrol 2014 Jan;36(1):80-92.

Sara Reyna, Puntip Tantiwong, Eugenio Cersosimo, R. A. DeFronzo, Apiradee Sriwijitkamol Nicolas Musi,. Short term exercise training improves insulin sensitivity but does not inhibit inflammatory pathways in immune cells from insulin resistant subjects Experimental Diabetes Research 2013 Jul;.

Fowler SP, Puppala S, Arya R, Chittoor G, Farook VS, Schneider J, Resendez RG, Upadhayay RP, VandeBerg J, Hunt KJ, Bradshaw B, Cersosimo E, VandeBerg JL, Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R. Genetic epidemiology of cardiometabolic risk factors and their clustering patterns in Mexican American children and adolescents: The SAFARI Study Human Genetics 2013 Jan;132(9):59-71.

Solis C, Triplitt C, Garduno-Garcia JD, Adams J, DeFronzo RA, Cersosimo C. Mechanisms of glucose lowering of DPP-4 inhibitor sitagliptin when used alone or with metformin in type 2 diabetes: A double tracer study Diabetes Care 2013 Jan;36:2756-2762.

Cersosimo E, Xu X, Musi N. Potential role of insulin signaling on vascular smooth muscle cell migration, proliferation, and inflammation pathways Am J Physiol Cell Physiol 2012 Feb;302(4):C652-C657.

Cersosimo E, Gastaldelli A, Cervera A, Wajcberg E, Sriwijilkamol A, Fernandez M, Zuo P, Petz R, Triplitt C, Musi N, Defronzo RA. Effect of exenatide on splanchnic and peripheral glucose metabolism in type 2 diabetic subjects J Clin Endocrinol Metab 2011 Jun;96(6):1763-1770.

Fernandez M, Gastaldelli A, Triplitt C, Hardies J, Casolaro A, Petz R, Tantiwong P, Musi N, Cersosimo E, Ferrannini E, Defronzo R. Metabolic Effects of Muraglitazar in Type 2 Diabetic Subjects Diabetes Obes Metab 2011 May;13:893-902.

Joya-Galeana J, Fernandez M, Cervera A, Reyna SM, Ghosh S, Triplitt C, Musi N, DeFronzo R, Cersosimo E. Effects of insulin and oral antidiabetic agents on glucose metabolism, vascular dysfunction and skeletal muscle inflammation in type 2 diabetic subjects Diabetes/Metabolism Research and Reviews 2011 Jan;27(4):373-382.

Associate Professor of Medicine, University of Texas Health Science Center, San Antonio, TX
Medical Director of Clinical Research, Texas Diabetes Institute, San Antonio, TX


Ph.D., Physiology, Vanderbilt University, 1985

M.D., Clinical Sciences,Universidade Federal Fluminense, 1975


Phone: (210) 358-7200