Please note: The University of Texas Health Science Center at San Antonio will now be called "UT Health San Antonio."

Search Program Faculty/Research

Christopher Frei, Pharm.D.

Chris frei 1


Dr. Christopher R. Frei is the Pharmacotherapy Division Head; one of five divisions in the UT Austin College of Pharmacy, and the only division located outside of Austin, in San Antonio. 

He is also the Director of the Pharmacotherapy Education and Research Center in the School of Medicine at the UT Health Science Center San Antonio. 

In 2015 he became the Program Director for the multidisciplinary joint Translational Science Ph.D. Program, involving four UT institutions in the Austin and San Antonio areas. The program recruits physicians, pharmacists, nurses, dentists, and others with professional doctoral degrees, and trains them to conduct innovative clinical and translational research. 

Dr. Frei’s research laboratory is currently pursuing two major research ventures. One is to build and analyze large patient cohorts using the national Veterans Affairs data repositories. 

The other is to conduct prospective clinical and translational studies in medical practices. Dr. Frei’s independent and collaborative research has been supported by AHRQ, NIH, PCORI, universities, professional societies, and the pharmaceutical industry. He has published more than 95 peer-reviewed papers in leading journals, including JAMA, JAMA Internal Medicine, the American Journal of Medicine, Chest, and Drugs. He has also given more than 400 scientific and educational presentations. 

He has been recognized as “Mentor of the Year” by the Texas Society of Health System Pharmacists, “Young Investigator of the Year” by the Society of Infectious Diseases Pharmacists, and “Distinguished Young Alumnus of the Year” by the UT Austin College of Pharmacy. 

He is a Board Certified Pharmacotherapy Specialist and a Fellow of the American College of Clinical Pharmacy and the American Association of Colleges of Pharmacy. Finally, he serves as an Ambassador for the NIH Loan Repayment Program.

Selected Publications 

Attridge RT, Frei CR, Restrepo MI, Lawson KA, Ryan L, Pugh MJ, Anzueto A, Mortensen EM. (2011). Guideline-concordant therapy and outcomes in healthcare-associated pneumonia. European Respiratory Journal. 38 (4), 878-887.

Mortensen EM, Nakashima B, Cornell J, Copeland LA, Pugh MJ, Anzueto A, Good C, Restrepo MI, Downs JR, Frei CR, Fine MJ. (2012). Population-based study of statins, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors on pneumonia-related outcomes. Clinical Infectious Diseases. 55 (11), 1466-1473.

Lee GC, Reveles KR, Attridge RT, Lawson KA, Mansi IA, Lewis JS 2nd, Frei CR. (2014). Outpatient antibiotic prescribing in the United States: 2000 to 2010. BMC Medicine. 12, 96.

Reveles KR, Juday TR, Labreche MJ, Mortensen EM, Koeller JM, Seekins D, Oramasionwu CU, Bollinger M, Copeland LA, Jones X, Frei CR. (2015). Comparative value of four measures of retention in expert care in predicting clinical outcomes and health care utilization in HIV patients. PLoS One. 10 (3), e0120953.

Forcade NA, Wiederhold NP, Ryan L, Talbert RL, Frei CR. (2012). Antibacterials as adjuncts to incision and drainage for adults with purulent methicillin-resistant Staphylococcus aureus (MRSA) skin infections. Drugs. 72 (3), 339-351.

Labreche MJ, Lee GC, Attridge RT, Mortensen EM, Koeller J, Du LC, Nyren NR, Treviño LB, Treviño SB, Peña J, Mann MW, Muñoz A, Marcos Y, Rocha G, Koretsky S, Esparza S, Finnie M, Dallas SD, Parchman ML, Frei CR. (2013). Treatment failure and costs in patients with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections: a South Texas Ambulatory Research Network (STARNet) study. Journal of the American Board of Family Medicine. 26 (5), 508-517.

Lee GC, Long SW, Musser JM, Beres SB, Olsen RJ, Dallas SD, Nunez YO, Frei CR. (2015). Comparative whole genome sequencing of community-associated methicillin-resistant Staphylococcus aureus sequence type 8 from primary care clinics in a Texas community. Pharmacotherapy. 35 (2), 220-228.

Mansi I, Frei CR, Pugh MJ, Makris U, Mortensen EM. (2013). Statins and musculoskeletal conditions, arthropathies, and injuries. Journal of the American Medical Association (JAMA) Internal Medicine. 173 (14), 1-10.

Schmidt T, Battafarano DF, Mortensen EM, Frei CR, Mansi I. (2013). Frequency of development of connective tissue disease in statin-users versus nonusers. American Journal of Cardiology. 112 (6), 883-888.

Mortensen EM, Halm EA, Pugh MJ, Copeland LA, Metersky M, Fine MJ, Johnson CS, Alvarez CA, Frei CR, Good C, Restrepo MI, Downs JR, Anzueto A. (2014). Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia. Journal of the American Medical Association (JAMA). 311 (21), 2199-2208.

Mansi I, Frei CR, Wang CP, Mortensen EM. (2015). Statins and new-onset diabetes mellitus and diabetic complications: a retrospective cohort study of U.S. healthy adults. Journal of General Internal Medicine. 30 (11), 1599-1610. 

Program Director, Translational Sciences Ph.D.program

Division Head of Pharmacotherapy, The University of Texas at Austin College of Pharmacy

Associate Professor, The University of Texas at Austin College of Pharmacy


M.S., Pharmacy, The University of Texas at Austin College of Pharmacy, 2003

Pharm.D., Pharmacy, The University of Texas Austin/The University of Texas Health Science Center San Antonio, 2001



Phone: (210) 567-8355