Please note: The University of Texas Health Science Center at San Antonio will now be called "UT Health San Antonio."

Search Program Faculty/Research

Christopher Frei, Pharm.D.

Chris frei 1


Dr. Christopher R. Frei is the Pharmacotherapy Division Head; one of five divisions in the UT Austin College of Pharmacy, and the only division located outside of Austin, in San Antonio. 

He is also the Director of the Pharmacotherapy Education and Research Center in the School of Medicine at the UT Health Science Center San Antonio. 

In 2015 he became the Program Director for the multidisciplinary joint Translational Science Ph.D. Program, involving four UT institutions in the Austin and San Antonio areas. The program recruits physicians, pharmacists, nurses, dentists, and others with professional doctoral degrees, and trains them to conduct innovative clinical and translational research. 

Dr. Frei’s research laboratory is currently pursuing two major research ventures. One is to build and analyze large patient cohorts using the national Veterans Affairs data repositories. 

The other is to conduct prospective clinical and translational studies in medical practices. Dr. Frei’s independent and collaborative research has been supported by AHRQ, NIH, PCORI, universities, professional societies, and the pharmaceutical industry. He has published more than 95 peer-reviewed papers in leading journals, including JAMA, JAMA Internal Medicine, the American Journal of Medicine, Chest, and Drugs. He has also given more than 400 scientific and educational presentations. 

He has been recognized as “Mentor of the Year” by the Texas Society of Health System Pharmacists, “Young Investigator of the Year” by the Society of Infectious Diseases Pharmacists, and “Distinguished Young Alumnus of the Year” by the UT Austin College of Pharmacy. 

He is a Board Certified Pharmacotherapy Specialist and a Fellow of the American College of Clinical Pharmacy and the American Association of Colleges of Pharmacy. Finally, he serves as an Ambassador for the NIH Loan Repayment Program.

Selected Publications 

Attridge RT, Frei CR, Restrepo MI, Lawson KA, Ryan L, Pugh MJ, Anzueto A, Mortensen EM. Guideline-concordant therapy and outcomes in healthcare-associated pneumonia. The European Respiratory Journal 2011;38:878-87.

Forcade NA, Parchman ML, Jorgensen JH, Du LC, Nyren NR, Trevino LB, Pena J, Mann MW, Munoz A, Trevino SB, Mortensen EM, Wickes BL, Pollock BH, Frei CRPrevalence, severity, and treatment of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections in 10 medical clinics in Texas: a South Texas Ambulatory Research Network (STARNet) study. Journal of the American Board of Family Medicine : JABFM 2011;24:543-50.

Forcade NA, Wiederhold NP, Ryan L, Talbert RL, Frei CRAntibacterials as adjuncts to incision and drainage for adults with purulent methicillin-resistant Staphylococcus aureus (MRSA) skin infections. Drugs 2012;72:339-51.

Mortensen EM, Nakashima B, Cornell J, Copeland LA, Pugh MJ, Anzueto A, Good C, Restrepo MI, Downs JR, Frei CR, Fine MJ. Population-based study of statins, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors on pneumonia-related outcomes. Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America 2012;55:1466-73.

Labreche MJ, Lee GC, Attridge RT, Mortensen EM, Koeller J, Du LC, Nyren NR, Trevino LB, Trevino SB, Pena J, Mann MW, Munoz A, Marcos Y, Rocha G, Koretsky S, Esparza S, Finnie M, Dallas SD, Parchman ML, Frei CRTreatment failure and costs in patients with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections: a South Texas Ambulatory Research Network (STARNet) study. Journal of the American Board of Family Medicine : JABFM 2013;26:508-17.

Mansi I, Frei CR, Pugh MJ, Makris U, Mortensen EM. Statins and musculoskeletal conditions, arthropathies, and injuries. JAMA Internal Medicine 2013;173:1-10.

Mortensen EM, Halm EA, Pugh MJ, Copeland LA, Metersky M, Fine MJ, Johnson CS, Alvarez CA, Frei CR, Good C, Restrepo MI, Downs JR, Anzueto A. Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia. JAMA 2014;311:2199-208.

8.Lee GC, Reveles KR, Attridge RT, Lawson KA, Mansi IA, Lewis JS, 2nd, Frei CROutpatient antibiotic prescribing in the United States: 2000 to 2010. BMC Medicine 2014;12:96.

Reveles KR, Juday TR, Labreche MJ, Mortensen EM, Koeller JM, Seekins D, Oramasionwu CU, Bollinger M, Copeland LA, Jones X, Frei CRComparative value of four measures of retention in expert care in predicting clinical outcomes and health care utilization in HIV patients. PLoS One 2015;10:e0120953.

Lee GC, Long SW, Musser JM, Beres SB, Olsen RJ, Dallas SD, Nunez YO, Frei CRComparative whole genome sequencing of community-associated methicillin-resistant Staphylococcus aureus sequence type 8 from primary care clinics in a Texas community. Pharmacotherapy 2015;35:220-8.

Program Director, Translational Sciences Ph.D.program

Division Head of Pharmacotherapy, The University of Texas at Austin College of Pharmacy

Assistant Professor, The University of Texas at Austin College of Pharmacy


M.S., Pharmacy, The University of Texas at Austin College of Pharmacy, 2003

Pharm.D., Pharmacy, The University of Texas Austin/The University of Texas Health Science Center San Antonio, 2001



Phone: (210) 567-8355