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Program Faculty/Research

Total results: 351

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Muhammed Abdul-Ghani, M.D., Ph.D.

The seminal studies of Dr. Muhammad Abdul-Ghani have helped define the role of progressive beta cell failure in the evolution...

Martin adamo

Martin Adamo, Ph.D.

Dr. Martin Adamo's lab studies insulin-like growth factor-I (IGF-I) synthesis and action throughout the life span. IGF-I is a...


Sunil Ahuja, M.D.

Medicine - Determinants of human disease: HIV, allergy, autoimmunity.

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Armen Akopian, Ph.D.

(Endodontics) – modulation of inflammatory and neuropathic pain

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Reto Asmis, Ph.D.

Biochemistry - Thiol oxidative stress and macrophage dysfunction in chronic inflammatory diseases.

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Dean Bacich, Ph.D.

Urology - Unique models of Prostate cancer initiation, progression, and metastasis.

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Yidong Bai, Ph.D.

Cellular and Structural Biology - Mitochondrial, respiratory chain, complex assembly, turnover, copy number control.

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Tiziano Barberi, Ph.D.

Texas Biomedical Research Institute - Human embryonic stem cells.

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Michael J. Beckstead, Ph.D.

(Cellular & Integrative Physiology) – electrophysiology of dopamine neurons; synaptic transmission and drug abuse

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Kelly Berg, Ph.D.

(Pharmacology) – G protein-coupled receptors, signal transduction, ligand functional selectivity


Manzoor Bhat, M.S., Ph.D.

(Cellular & Integrative Physiology) – molecular neuron-glia interactions, synaptic development and neurological disorders

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Alexander J.R. Bishop, D. Phil.

Greehey Children's Cancer Research Institute - Genomic instability, DNA repair, cell signaling, cancer and aging.

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Thomas G. Boyer, Ph.D.

(Molecular Medicine) – transcriptional regulation and DNA repair in neuronal cell systems


Andrew Brenner, M.D./Ph.D.

(Cancer Therapy and Research Center) – Neuro-oncology; overcoming resistance to cancer therapy driven by the hypoxic microenviro

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Robert Brenner, Ph.D.

(Cellular & Integrative Physiology) – Integrative physiology and biophysics of ion channel structure and cellular signaling


Melanie Carless, Ph.D.

(TX Biomed Res Inst) – epigenetic mechanisms and miRNAs associated with neuropsychiatric disorders

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José E. Cavazos, M.D., Ph.D.

(Neurology) – hippocampal plasticity; mechanisms of neuronal hyperexcitability, epilepsy

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Bandana Chatterjee, Ph.D.

Molecular Medicine - Gene regulation, nuclear receptors, cancer biology, environmental carcinogenesis.

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Xiao-Dong Chen, M.D., Ph.D.

Comprehensive Dentistry - Stem cell fate in tissue regeneration.


Yidong Chen, Ph.D.

Epidemiology and Biostatistics - Bioinformatics, statistical, and systems biology methods for modeling tumor phenotype.

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Robert A. Clark, M.D.

Medicine - Neutrophil phagocytosis, microbial killing, tissue injury, cell signaling, reactive oxygen species.

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William Clarke, Ph.D.

(Pharmacology) – molecular and cellular mechanisms of drug efficacy and differential signal transduction

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Gregory Collins, Ph.D.

(Pharmacology) – determinants of drug-seeking and drug-taking of abused substances, such as “bath salts”

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Marcel M. Daadi, Ph.D.

(TX Biomed Res Inst) – develop neural stem cells for therapeutic use in Parkinson’s and other diseases

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Patricia L. Dahia, M.D., Ph.D.

Medicine - Genetics of cancer and oncogenic pathways.

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Lynette C. Daws, Ph.D.

(Cellular & Integrative Physiology) – regulation of monoamine transporters, psychotherapeutic drug effects

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Lily Q. Dong, Ph.D.

Cellular and Structural Biology - Adiponectin signaling in obesity and diabetes.

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Alfred Fisher, M.D., Ph.D.

Medicine - Clinical geriatrics and the use of the nematode, Caenorhabditis elegans in aging research.

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Paul Fitzpatrick, Ph.D.

(Biochemistry and Structural Biology) – Regulation of enzymes involved in neurotransmitter biosynthesis

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Charles P. France, Ph.D.

(Pharmacology) – behavioral and pharmacological factors influencing the abuse liability of drug


Alan Frazer, Ph.D.

(Pharmacology) – mechanisms of action of antidepressant drugs, regulation of serotonin transporter function

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James W. Freeman, Ph.D.

Medicine - Pathobiology and therapy of pancreatic cancer.

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Bess Frost, Ph.D.

(Cell Systems and Anatomy) – mechanisms of neurodegeneration in drosophila models and Alzheimer’s Disease

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Maria E. Gaczynska, Ph.D.

Molecular Medicine - Proteolytic systems in cancer and aging.

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Veronica Galvan, Ph.D.

Physiology - Alzheimer's disease, nervous system, aging, mTOR pathway, stem cell.


Lisa R. Gerak, Ph.D.

(Pharmacology) – behavioral pharmacology of the GABAA receptor, with an emphasis on the effects of ethanol and neuroactive stero

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Rita Ghosh, Ph.D.

Urology - Melanoma, DNA damage, genitourinary and skin cancer.


Brett Ginsburg, Ph.D.

(Psychiatry) – Mechanisms of alcohol abuse and recovery; behavioral pharmacology of synthetic cannabinoids


Andrea Giuffrida, Ph.D.

(Pharmacology) – Cannabinoid regulation of basal ganglia function and implications for Parkinson’s disease and Schizophrenia


Randy Glickman, Ph.D.

(Ophthalmology) – retinal physiology and neurobiology, biomedical optics

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Kenneth M. Hargreaves, D.D.S., Ph.D.

(Endodontics) – neuropharmacology of primary nociceptors and pain sensitivity

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Stephen E. Harris, Ph.D.

Periodontics - BMP2 mechanisms and osteocyte function.

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P. John Hart, Ph.D.

(Cellular & Integrative Physiology) – cellular and molecular processes in the pathogenesis of Alzheimer's disease

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E. Paul Hasty, Ph.D.

Molecular Medicine - Genetics of chromosomal metabolism with importance toward cancer and aging.

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Tim H.-M. Huang, Ph.D.

Molecular Medicine - Cancer epigenetics.

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Nathaniel A. Jeske, Ph.D.

(Oral and Maxillofacial Surgery) – biochemical modulation of peripheral pain in nociceptive neurons by regulation of TRPV1 chann

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Jean Jiang, Ph.D.

Biochemistry - Intercellular and intracellular signaling, amino acid transport.

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Victor Jin, Ph.D.

Molecular Medicine - Computational epigenetics and bioinformatics.

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Teresa L. Johnson-Pais, Ph.D.

Pediatrics - Genetic alterations in cancer tumorigenesis.

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David Kadosh, Ph.D.

Microbiology - Cell morphology, filamentous growth, fungal pathogenesis, gene regulation, genomics.


Jun Hee Kim, Ph.D.

(Cellular & Integrative Physiology) – myelination and regulation of neuronal excitability and synaptic transmission

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Wouter Koek, Ph.D.

(Psychiatry) – animal models of drug abuse, subjective effects and treatments

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Erzsebet Kokovay, Ph.D.

(Cell & Structural Biology) – molecular and cellular regulation of neural stem cells and adult neurogenesis

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Ellen B. Kraig, Ph.D.

Cellular and Structural Biology - Effects of aging and infection on immunity and autoimmunity.

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A. Pratap Kumar, Ph.D.

Urology - Molecular targets, cancer therapy.

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Eileen M. Lafer, Ph.D.

(Biochemistry and Structural Biology) – synaptic vesicle proteins; mechanisms of synaptic vesicle exo- and endocytosis

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Richard J. Lamb, Ph.D.

(Psychiatry) – behavioral pharmacology and neurobiology of drug addiction and treatment

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Pamela L. Larsen, Ph.D.

Cellular and Structural Biology - Metabolism, stress resistance, aging and Caenorhabditis elegans development.


Robin J. Leach, Ph.D.

Cellular and Structural Biology & Urology - Genetics of complex diseases and biomarkers for cancer.

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James D. Lechleiter, Ph.D.

(Cell Systems and Anatomy) – mitochondrial calcium regulation in cell death and survival in the aging process

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Hye Young Lee, Ph.D.

(Cellular & Integrative Physiology) – ion channel dysregulation in mouse models of FXS and other developmental disorders

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Sang Eun Lee, Ph.D.

Molecular Medicine - DNA repair and cancer.

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Donna M. Lehman, Ph.D.

Cellular and Structural Biology - Public health genomics, diabetes.

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Senlin Li, Ph.D.

(Medicine) – hematopoietic stem cell-derived macrophage gene therapy for neurodegenerative diseases

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Daniel J. Lodge, Ph.D.

(Pharmacology) – Hippocampal and other afferent regulation of mesolimbic dopamine activity

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Philip LoVerde, Ph.D.

Biochemistry - Molecular, genetic and immunological investigation of the human blood fluke, Schistosoma mansoni.

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David A. Morilak, Ph.D.

(Pharmacology) – brain norepinephrine in the stress response, anxiety and antidepressant drug action

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James L. ‘Jay’  Morris, Jr.,  Ph.D.

Molecular Medicine - Natural products in cancer treatment and prevention.

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Bruce Nicholson, Ph.D.

Biochemistry - Cell communication; gap junction channel structure, permeability and gating.

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Luke Norton, Ph.D.

Diabetes - Molecular biology, genetics, and physiology of insulin resistance and type-2-diabetes.

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Jason O’Connor, Ph.D.

(Pharmacology) – Tryptophan metabolism and mechanisms linking neuroinflammation and depression

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Denise O’Keefe, Ph.D.

Urology - Epigenetic regulation in prostate cancer.


Michael Olivier, Ph.D.

Genomic and proteomic analyses in human disease.

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Babatunde “Kay” Oyajobi, M.B.,B.S, Ph.D., M.B.A.

Cellular and Structural Biology - Ubiquitin-proteasome pathway, non-invasive small animal imaging.

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Jean Patterson, Ph.D.

Texas Biomedical Research Institute - Virology and immunology.

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Martin Paukert, M.D.

(Cellular & Integrative Physiology) – Role of calcium signaling and neuron-astroglial interactions in neuromodulation and arousa

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Luiz O. Penalva, Ph.D.

Greehey Children's Cancer Research Institute - Post-transcriptional regulation and RNA binding proteins.


Alexander Pertsemlidis, Ph.D.

Greehey Children's Cancer Research Institute & Pediatrics - MicroRNA in cancer.

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Jason Pugh, Ph.D.

(Cellular & Integrative Physiology) – Axonal plasticity, cellular computation and signal processing in neural circuits

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Qitao Ran, Ph.D.

(Cell Systems and Anatomy) – role of mitochondrial oxidative stress in aging and Alzheimer’s Disease

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Hai Rao, Ph.D.

Molecular Medicine - Ubiquitin regulated proteolysis, protein quality control, prion diseases.


Manjeet K. Rao, Ph.D.

Greehey Children's Cancer Research Institute - Pediatric cancers, microRNA, RNAi, transcription.

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Pothana Saikumar, Ph.D.

Pathology - Cell injury, cell death, oncogenes.


Adam Salmon, Ph.D.

Barshop/Molecular Medicine - Oxidative stress, mTOR, rapamycin, metabolism, and aging.

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Naomi Sayre, Ph.D.

(Neurosurgery) – role of astrocyte lipoprotein metabolism in recovery from stroke and traumatic brain injury


Mark S. Shapiro, Ph.D.

(Cellular & Integrative Physiology) – ion channel physiology; regulation by intracellular signaling pathways and excitability

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Z. Dave Sharp, Ph.D.

Molecular Medicine - The target of rapamycin in cancer and aging.

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Yuzuru Shiio, M.D., Ph.D.

Biochemistry - Quantitative proteomics, ubiquitin ligases, protein secretion, senescence, cancer.

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Paula K. Shireman, M.D.

Surgery- Inflammatory-mediated mechanisms of angiogenesis.

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Gek-Ming Sia, Ph.D.

(Pharmacology) – neurodevelopment, cortical synapse and circuit formation, synaptogenesis

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James D. Stockand, Ph.D.

(Cellular & Integrative Physiology) – structure, function and regulation of ENaC/Degenerin sodium ion channels

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J. Randy Strong, Ph.D.

(Pharmacology) – role of catecholamines in aging; regulation of tyrosine hydroxylase gene expression

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LuZhe Sun, Ph.D.

Cellular and Structural Biology - Cancer biology, signal transduction, cell cycle, senescence, experimental therapeutics.

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Rajeshwar R. Tekmal, Ph.D.

Obstetrics and Gynecology - Growth factor/hormone crosstalk, signal transduction, steroid hormone co-activation.

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Glenn M. Toney, Ph.D.

(Cellular & Integrative Physiology) – cellular, molecular and integrative mechanisms of sympathetic nervous system function


Ratna K. Vadlamudi, Ph.D.

Obstetrics and Gynecology - Nuclear receptors, hormones, chromatin regulation, epigenetics, breast cancer.


Christi A. Walter, Ph.D.

Cellular and Structural Biology - DNA repair, mutagenesis, mitochondria, transgenic mice, aging, spermatogenic cells.

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Pei Wang, Ph.D.

Cellular and Structural Biology - Pancreatic diseases: Diabetes and pancreatic ductal adenocarcinoma.

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Michael J. Wargovich, Ph.D.

Molecular Medicine - Cancer chemoprevention and drug discovery.

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David S. Weiss, Ph.D.

(Cellular & Integrative Physiology) – GABA receptor structure and function


Kexin Xu, Ph.D.

Molecular Medicine - Epigenetic regulatory programs in human disease.


Zhenming “Jack” Xu, Ph.D.

Microbiology and Immunology - Host immune response to infection, cancer and vaccination.

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P. Renee Yew, Ph.D.

Molecular Medicine - Cell cycle regulation and ubiquitination in cancer and human disease.


Guangming Zhong, M.D., Ph.D.

Microbiology - Microbial manipulation of mammalian cell apoptosis, Infection and Immunity, vaccines.