Published on the cover of PLOS
Community acquired pneumonia (CAP) is a common respiratory illness, which if detected and treated early, causes few health complications. However, elderly individuals and individuals with weakened immune systems can develop a severe form CAP that can lead to severe sepsis and death. Cardiac complications are a common cause of death in approximately 20% of these individuals. Armand Brown, working in Dr. Carlos J. Orihuela’s lab, has been studying the interactions between Streptococcus pneumoniae and the heart during severe pneumonia. His article in the September issue of PLoS Pathogens details a remarkable discovery that can potentially improve the treatment of severe pneumonia.